{"id":3115,"date":"2015-06-24T03:28:30","date_gmt":"2015-06-24T00:28:30","guid":{"rendered":"https:\/\/dentplus.com.tr\/V2\/?p=3115"},"modified":"2015-06-24T03:28:55","modified_gmt":"2015-06-24T00:28:55","slug":"cocukta-floridli-dis-macunu-kullaniminin-yararlari-ve-olasi-rikleri","status":"publish","type":"post","link":"https:\/\/dentplus.com.tr\/V2\/cocukta-floridli-dis-macunu-kullaniminin-yararlari-ve-olasi-rikleri\/","title":{"rendered":"\u00c7ocukta Floridli Di\u015f Macunu Kullan\u0131m\u0131n\u0131n yararlar\u0131 ve olas\u0131 riskleri\u2026"},"content":{"rendered":"

1940 lar\u0131n ba\u015f\u0131nda sular\u0131n floridlendirilmesinin ke\u015ffinden sonra \u00e7\u00fcr\u00fckten korumada floridlerin kullan\u0131m\u0131 en pop\u00fcler y\u00f6ntemlerden biri olmu\u015ftur. Ancak a\u011f\u0131z sa\u011fl\u0131\u011f\u0131n\u0131 iyile\u015ftirilmesinde kullan\u0131lan flor iyonlar\u0131 \u00e7\u00fcr\u00fc\u011fe kar\u015f\u0131 koruyucu etkilerinin yan\u0131nda floroz geli\u015fme riskini de i\u00e7erisinde bar\u0131nd\u0131r\u0131r. Bu a\u00e7\u0131dan \u00e7ocuklarda flor iyonu ta\u015f\u0131yan \u00fcr\u00fcnlerin kullan\u0131m\u0131n\u0131n takibi \u00f6nemlidir. G\u00fcn\u00fcm\u00fcz \u00e7ocuklar\u0131 yarar ve zararlar\u0131 aras\u0131nda ki dengenin tam kesinlik kazanmad\u0131\u011f\u0131 flor iyonunu \u00e7ok \u00e7e\u015fitli kaynaklardan alabilmektedir.<\/p>\n

\u00c7ocuklarda \u00e7\u00fcr\u00fckten korunmada kullan\u0131lan florid i\u00e7eren a\u011f\u0131z sa\u011fl\u0131\u011f\u0131 \u00fcr\u00fcnlerinin g\u00fcvenirli\u011fi \u00fczerinde \u00f6zellikle son y\u0131llarda giderek artan bi\u00e7imde tart\u0131\u015fmalar\u0131n g\u00fcndeme gelmesi bir\u00e7ok \u00fclkeyi olas\u0131 toksik etkilere kar\u015f\u0131 florid kullan\u0131m\u0131 konusunda farkl\u0131 yakla\u015f\u0131mlara y\u00f6nelmi\u015ftir.<\/p>\n

Bu derleme, floridli di\u015f macunlar\u0131n\u0131n kullan\u0131m\u0131 \u00fczerinde ki tart\u0131\u015fmalara y\u00f6nelik olarak flor iyonunun metabolizma \u00fczerinde ki etkileri ve olas\u0131 toksik etkileri esas al\u0131narak bu alanda yap\u0131lan \u00e7al\u0131\u015fmalar\u0131n sunulmas\u0131n\u0131 ama\u00e7lamaktad\u0131r.<\/p>\n

Flor iyonu kaynaklar\u0131 ve emilimi<\/strong><\/p>\n

\"florur\"A\u011f\u0131z yolu ile al\u0131nan floridin ana kaynaklar\u0131 aras\u0131nda su, di\u011fer beslenme kaynaklar\u0131 (\u00e7ay, floridli su ile haz\u0131rlanan yiyecek ve i\u00e7ecekler), floridli tablet\/damlalar, \u00f6zellikle ABD ve \u0130ngiltere de yayg\u0131n olarak kullan\u0131lan \u00e7e\u015fitli preparatlar, \u00e7ocuklar taraf\u0131ndan istemsiz yutulan floridli di\u015f macunlar\u0131 ve gargaralar say\u0131labilir. Bununla birlikte, baz\u0131 bireyler i\u015fleri gere\u011fi veya tedavi dozu olarak (otoskleroz ve osteoporoz tedavisinde) flor iyonunsa maruz kal\u0131rlar.<\/p>\n

Bir florid par\u00e7as\u0131 yutuldu\u011funda, baz\u0131 flor iyonlar\u0131 a\u011f\u0131zda ve di\u015flerde iyon de\u011fi\u015fimi yoluyla tutunurken, \u00e7o\u011fu iyonize olmam\u0131\u015f hidrojen florid \u015feklinde mide ve ince barsaktan %100 emilir. Emilen flor iyonu miktar\u0131n\u0131 bir dizi de\u011fi\u015fken etkiler, bunlar aeas\u0131nda floridin tipi, ya\u015f, pH ko\u015fullar\u0131, magnezyum, kalsiyum ve di\u011fer iyon konsantrasyonlar\u0131 say\u0131labilir. S\u00fcrekli kullan\u0131lan floridli preparatl\u0131n v\u00fccutta olu\u015fturdu\u011fu etkiler, s\u00fcrekli floridli i\u00e7me suyu t\u00fcketilmesi ile benzerdir.<\/p>\n

Di\u015f macunun arkas\u0131nda kulllan\u0131m uyar\u0131lar\u0131nda yutulmamams\u0131 ve \u201cbezelye\u201d b\u00fcy\u00fckl\u00fc\u011f\u00fcnde kullan\u0131lmas\u0131 yaz\u0131lm\u0131\u015f olsa da, reklamlarda f\u0131r\u00e7a boyutlar\u0131nda tepeleme uzanan \u015fekilde vurgulanmaktad\u0131r, \u00fcreticiler \u00a0k\u00f6p\u00fcren, meyveli, \u015fekerli tatlar\u0131 sat\u0131\u015fa sunmaktad\u0131r. \u00c7ocuklar\u0131n kullan\u0131ld\u0131\u011f\u0131 \u00e7ekici reklamlarda ki tatlar yutma refleksinin zay\u0131f geli\u015fti\u011fi k\u00fc\u00e7\u00fck \u00e7ocuklarda tehlikeli olup, f\u0131r\u00e7alar\u0131na devaml\u0131 b\u00fcy\u00fck miktarda macun s\u0131karlar. \u00c7ocuklar\u0131n herg\u00fcn ciddi miktarda floridi yaln\u0131zca yuttu\u011funu macunla ald\u0131\u011f\u0131n\u0131 g\u00f6steren \u00e7al\u0131\u015fmlar s\u00fcrpriz de\u011fildir. Journal of Public Health Dentistry\u2019ye g\u00f6re hemen hemen t\u00fcm ara\u015ft\u0131r\u0131c\u0131lar baz\u0131 \u00e7ocuklar\u0131n \u00f6nerilen total g\u00fcnl\u00fck dozun \u00fczerinde floridi yaln\u0131zca di\u015f macunundan yuttuklar\u0131n\u0131 belitmi\u015fleridr.<\/p>\n

Baz\u0131 bireylerde floridli di\u015f macunu kullan\u0131m\u0131 a\u011f\u0131z \u00e7evresinde ki dermatiti \u015fiddetlendirebilir(a\u011f\u0131z \u00e7evresinde ki ciltte rozase benzeri bir k\u0131zar\u0131kl\u0131k) Genellikle 20-50 ya\u015flar\u0131 aras\u0131nda ki kad\u0131nlarda g\u00f6r\u00fclen bu semptomlar\u0131n florid i\u00e7ermeyen bir macunun kullan\u0131lmas\u0131 ile birka\u00e7 hafta i\u00e7erisinde d\u00fczelebilir. Macunlarda ki floridin stomatite de yol a\u00e7abilece\u011fi bildirilmi\u015ftir. Ancak en \u00f6nemlisi fazla miktarda yutulmas\u0131 kan \u015fekeri ve ins\u00fclin oranlar\u0131nda etki olu\u015fturabilmektedir.<\/p>\n

Flor iyonunun v\u00fccuda girmesinin sa\u011fl\u0131k \u00fczerine olan etkileri y\u0131llar i\u00e7erisinde bir\u00e7ok ara\u015ft\u0131rmac\u0131 taraf\u0131ndan incelenmi\u015ftir. Ancak bu ara\u015ft\u0131rmalar\u0131n metodolojilerin bile tam olarak netlik kazanmam\u0131\u015f olmas\u0131 bu alanda kar\u015f\u0131la\u015f\u0131lan g\u00fc\u00e7l\u00fckleri ortaya koymaktad\u0131r.<\/p>\n

SA\u011eLIK \u00dcZER\u0130NE OLAN ETK\u0130LER\u2026<\/strong><\/p>\n

Di\u015f \u00c7\u00fcr\u00fc\u011f\u00fc:<\/strong><\/p>\n

\"denrplus_cocuk_dis_sagligi\"Flor iyonu ile di\u015f \u00e7\u00fcr\u00fc\u011f\u00fc aras\u0131nda ki kompleks ili\u015fki hen\u00fcz tam olarak anla\u015f\u0131lmam\u0131\u015f olsa da, mevcut halde \u00fc\u00e7 ana yolla etkiler, geli\u015fim s\u0131ras\u0131nda minenin kimyasal yap\u0131s\u0131n\u0131 iyile\u015ftirmesi, asit ataklara daha diren\u00e7li hale getirmesi, iyi kalitede mine kristal remineralizasyonun desteklenmesi ve plak bakterilerinin asit \u00fcretme becerilerinin azalt\u0131lmas\u0131 yolu ile olabilir.<\/p>\n

Floridli di\u015f macunlar\u0131n\u0131n 1960\u2019larda ke\u015ffinden sonra kullan\u0131mlar\u0131n\u0131n yayg\u0131n hale gelmesi ile \u00e7\u00fcr\u00fckten korunmada ki etkinli\u011fi sosyal s\u0131n\u0131flar aras\u0131nda ki farkl\u0131l\u0131\u011fa ba\u011fl\u0131 olarak de\u011fi\u015fiklik g\u00f6stermi\u015ftir. ABD\u2019de ya\u015fayan \u00e7ocuklar aras\u0131nda \u0130ngiltere\u2019ye oranla daha fazla dental floroz g\u00f6r\u00fclm\u00fc\u015ft\u00fcr. Sular\u0131n floridlendi\u011fi b\u00f6lgelerde \u00e7ocuklar\u0131n %7-36 kadar\u0131na \u00e7ocuk doktorlar\u0131 taraf\u0131ndan uygun olmayacak bi\u00e7imde re\u00e7etelendirilmi\u015f florid tabletleri kulland\u0131r\u0131lm\u0131\u015ft\u0131r. \u0130ste\u011fe ba\u011fl\u0131 kullan\u0131lan floridli \u00fcr\u00fcnlerin, florozda ki etkinli\u011finin y\u00fcksek oldu\u011funu belirterek ABD\u2019de d\u00fc\u015f\u00fck flor\u00fcr i\u00e7eren di\u015f macunlar\u0131nda oldu\u011fu belirtilmi\u015ftir.<\/p>\n

Kemik Sa\u011fl\u0131\u011f\u0131:<\/strong><\/p>\n

Sular\u0131n floridlerin b\u00f6lgelerde ya\u015fayanlar\u0131n belirli anotomik kemik k\u0131r\u0131klar\u0131 epifiz kaymalar\u0131n\u0131 ve osteosklerozu i\u00e7erir.<\/p>\n

Kanser:<\/strong><\/p>\n

Kansere yol a\u00e7an bir \u00e7ok genetoksik etken direk yada di\u011fer mekanizmalar ile etkilidir. Mesela h\u00fccre b\u00f6l\u00fcnmesini uyararak. B\u00fct\u00fcn olarak bak\u0131ld\u0131\u011f\u0131nda, floridin insanda genetoksik olabilece\u011fi kan\u0131t\u0131 bulunamam\u0131\u015ft\u0131r. Yine de floridin osteoblastlar \u00fczerinde olas\u0131 miktocenik etkilerine kar\u015f\u0131 yayg\u0131nl\u0131\u011f\u0131n\u0131n ara\u015ft\u0131r\u0131lmas\u0131 ve tedbirin elden b\u0131rak\u0131lmamas\u0131 gerekmektedir.<\/p>\n","protected":false},"excerpt":{"rendered":"

1940 lar\u0131n ba\u015f\u0131nda sular\u0131n floridlendirilmesinin ke\u015ffinden sonra \u00e7\u00fcr\u00fckten korumada floridlerin kullan\u0131m\u0131 en pop\u00fcler y\u00f6ntemlerden biri olmu\u015ftur. Ancak a\u011f\u0131z sa\u011fl\u0131\u011f\u0131n\u0131 iyile\u015ftirilmesinde kullan\u0131lan flor iyonlar\u0131 \u00e7\u00fcr\u00fc\u011fe kar\u015f\u0131 koruyucu etkilerinin yan\u0131nda floroz geli\u015fme riskini de i\u00e7erisinde bar\u0131nd\u0131r\u0131r. Bu a\u00e7\u0131dan \u00e7ocuklarda flor iyonu ta\u015f\u0131yan \u00fcr\u00fcnlerin kullan\u0131m\u0131n\u0131n takibi \u00f6nemlidir. G\u00fcn\u00fcm\u00fcz \u00e7ocuklar\u0131 yarar ve zararlar\u0131 aras\u0131nda ki dengenin tam kesinlik kazanmad\u0131\u011f\u0131Leer M\u00e1s<\/p>\n","protected":false},"author":1,"featured_media":3116,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[358,233,230],"tags":[301,362,336,296,435,361,360,359],"class_list":["post-3115","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cocuklar-ve-dis","category-dis-curugu","category-dis-eti-hastaliklari","tag-bursa-dis-doktoru","tag-cocuk-dis-sagligi","tag-cocuk-ve-dis","tag-dis-bakimi","tag-dis-curugu","tag-dis-macunu-ve-flor","tag-flor","tag-florid"],"_links":{"self":[{"href":"https:\/\/dentplus.com.tr\/V2\/wp-json\/wp\/v2\/posts\/3115","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dentplus.com.tr\/V2\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dentplus.com.tr\/V2\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dentplus.com.tr\/V2\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dentplus.com.tr\/V2\/wp-json\/wp\/v2\/comments?post=3115"}],"version-history":[{"count":2,"href":"https:\/\/dentplus.com.tr\/V2\/wp-json\/wp\/v2\/posts\/3115\/revisions"}],"predecessor-version":[{"id":3120,"href":"https:\/\/dentplus.com.tr\/V2\/wp-json\/wp\/v2\/posts\/3115\/revisions\/3120"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dentplus.com.tr\/V2\/wp-json\/wp\/v2\/media\/3116"}],"wp:attachment":[{"href":"https:\/\/dentplus.com.tr\/V2\/wp-json\/wp\/v2\/media?parent=3115"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dentplus.com.tr\/V2\/wp-json\/wp\/v2\/categories?post=3115"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dentplus.com.tr\/V2\/wp-json\/wp\/v2\/tags?post=3115"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}